These results suggest that ca2 + and cam were involved in hs genes expression likely thlough regulating the activity of hsr some studies have suggested that hsp70 is a negative regulatory factor . it represses activity of hsf by formation of complex with hsf under non - heat - shock condition 前人的研究表明, hsp70在热激基因表达中起负调节剂作用,在非热激条件下,它通过与hsf结合成复合体抑制hsf的活性。